NeoBona

neoBona is a simple and reliable prenatal genetic test. With a detection rate higher than 99% for Down's, Edward's and Patau syndromes, it provides accurate and reliable results.

A safe way to detect genetic disorders

neoBona only requires a single blood sample from the mother, making it a safe, simple, and reliable screening option. It can detect chromosomal abnormalities such as Down’s syndrome, Edward’s syndrome, and Patau syndrome with more than 99% certainty.

neoBona is a genetic screening test that can only be prescribed by your physician.

Speak to a doctor about neoBona

Safe and suitable for all pregnancies

neoBona is a non-invasive prenatal test which means that a single blood test from the mother is all that is needed to help detect possible genetic disorders. Unlike other prenatal tests, neoBona is completely non-invasive and carries no risk to the mother or foetus. It is suitable for all types of pregnancies, including IVF, donation, and vanishing or non-evolving foetuses and can be carried out from the 10th week of pregnancy onwards

The most advanced non-invasive prenatal test

neoBona was developed with Illumina, a world leader in DNA sequencing. By integrating state-of-the-art technology and world-class expertise, neoBona is able to accurately detect the most frequent chromosomal abnormalities in pregnancy with an accuracy higher than 99%. neoBona is able to detect these by studying the cell-free foetal DNA present in maternal blood.

Backed by SYNLAB's extensive team of medical professionals and genetics experts, you can trust that neoBona is the best option for reliable results and early detection

neoBona has several benefits, including:

Confidence

neoBona brings confidence to parents from the 10th week of pregnancy. It allows the detection of chromosomal abnormalities in the fetus. It is a non-invasive test with no risk to the future baby.

Convenience

Through SYNLAB, you have access to Europe's largest network of blood collection points.

Accuracy

Conventional first-trimester screening consists of blood and ultrasound analysis and provides a statistical index of risk. neoBona directly analyses cell-free fetal DNA and so provides greater accuracy, better detection, and fewer false positives.

Sensitivity

The sensitivity of a conventional screening is 90%, meaning that out of every 100 fetuses with Down's syndrome (trisomy 21), 10 would not be detected (false negatives). The overall sensitivity of neoBona is greater than 99% for Downs, Edward’s and Patau syndromes (trisomies 21, 18 and 13)

Specificity

Out of every 100 healthy pregnancies, five are incorrectly classified as high risk, leading to anxiety, counseling and further testing. The high specificity of neoBona reduces the number of false positive results to less than 1 in 1,500 pregnancies, reducing anxiety and unnecessary prenatal diagnosis

Chromosomal abnormalities detected through neoBona:

neobona detects the most frequent trisomies. A trisomy is caused by the presence of an additional copy of a chromosome instead of the normal two. neoBona detects the following trisomies;

Trisomy 21 (Down syndrome)

Children affected by this can have mild to moderate intellectual impairment, heart defects, and/or other disorders

Trisomy 18 (Edwards syndrome)

Affected infants typically have severe malformation and mental impediments and rarely survive beyond one year of age.

Trisomy 13 (Patau syndrome)

Infants with Patau syndrome have severe mental impediments can exhibit severe congenital heart malformations and other pathologies, and rarely survive beyond one year of age.

Klinefelter's syndrome

Aaects males when the normal male karyotype, 46, XY, has at least one extra E chromosome. It is characterized by small testes, low or no sperm cells, breast buds in puberty, and behavioral problems.

Turner's syndrome

The absence of a single X chromosome in the female. During childhood, girls may have short stature, and in later life, they have problems with puberty and fertility.

For medical practitioners

The most accurate non-invasive prenatal test.

SYNLAB is a pioneer in prenatal molecular diagnosis, and due to the incorporation of new scientific advances, we are able to offer neoBona a state-of-the-art non-invasive prenatal test backed by the expertise and reliability of one of Europe's leading laboratories.

neoBona was developed with Illumina, a world leader in DNA sequencing. By integrating state-of-the-art technology and world-class expertise, neoBona is able to accurately detect the most frequent chromosomal abnormalities in pregnancy with an accuracy higher than 99%. It uniquely analyses cell-free DNA fragment size to improve the accuracy of the result

neoBona integrates the power of cutting-edge DNA sequencing with innovative prenatal testing.
choose the most advanced non-invasive prenatal test for your patients.

Book a neoBona test